Abstract: Traditional binary confrontat ion of  practice-cognition is metaphysical and self-contradictory.With ontological significance of  field of vision and of position  for practical materialism; the practice is one only coupled by cognizing and trasnforming. In overcoming sorts of limitations in study of practical materialism, in strength-ening the ties between practice and dire straits of mankind, between practice and ultimate concern of mankind, in gaining a clear idea of certain basic problems in the view of communicant practice, such as communication, intersubjectivity, generally speaking, in unifying practical materialism, the sublation of binary c onfrontation of practice- cognition will surely play an important part.

Key words: binary confrontation, query, identity, sublate, significance