Abstract:

Agnosticism，as core content in the fundamental issues of philosophy，reveals multiple contradictions in epistemology.However，it also gets itself into dilemma.When it declares that the world is unknown，it has been a Gnosticism.It denies the commensurability of consciousness，but finally falls into the stereotype of mysticism.The blind spot of it lies in that it is restricted the scope of experience，and denies the objective reality outside consciousness，shielding social consciousness with individual consciousness.In vain，Hegel tries to solve the difficult problem of Agnosticism with speculative dialectics；Marx's philosophy places social practice to change the maze of Agnosticism，and illustrates new principles of philosophical interpretation.

Key words: agnosticism, essence, speculative, social practice